HitPredict

Interactor 1: CALM (P06787)
Calmodulin (CaM)
Gene: CMD1

Interactor 2: PP2B2 (P14747)
Serine/threonine-protein phosphatase 2B catalytic subunit A2 (EC 3.1.3.16) (Calcineurin A2) (Calmodulin-binding protein 2)
Gene: CMP2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.80	0.847

Property	Details
Experiments	1651503, 11474067, 11805837, 16554755, 37968396, 16429126
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	EF-hand_7~Metallophos
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 147 Sc			1 604
+	Sc
		420231 CALM_YEAST (1-147): 4.58e-47: 151: 100.00		PP2B1_YEAST (49-590): 0: 706: 65.93
+	Dm
		819188 CALL_DROME (11-76): 3.67e-17: 74.6: 37.88		PP2B1_DROME (59-576): 0: 694: 52.82
+	Hs
		483921 CALM1_HUMAN (80-147): 4.86e-12: 61.3: 40.58		PP2BA_HUMAN (65-582): 0: 700: 49.81
+	Hs
		483996 CALM2_HUMAN (80-147): 4.86e-12: 61.3: 40.58		PP2BA_HUMAN (65-582): 0: 700: 49.81
+	Hs
		484113 CALM3_HUMAN (80-147): 4.86e-12: 61.3: 40.58		PP2BA_HUMAN (65-582): 0: 700: 49.81
+	Hs
		483899 CALM1_HUMAN (80-147): 4.86e-12: 61.3: 40.58		PP2BB_HUMAN (67-583): 0: 691: 49.53
+	Hs
		483972 CALM2_HUMAN (80-147): 4.86e-12: 61.3: 40.58		PP2BB_HUMAN (67-583): 0: 691: 49.53
+	Hs
		484057 CALM3_HUMAN (80-147): 4.86e-12: 61.3: 40.58		PP2BB_HUMAN (67-583): 0: 691: 49.53
+	Dm
		906741 CALM_DROME (80-147): 7.11e-12: 61: 40.58		PP2B3_DROME (60-585): 0: 689: 48.79
+	Hs
		483985 CALM2_HUMAN (80-147): 4.86e-12: 61.3: 40.58		PP2BC_HUMAN (64-583): 0: 685: 48.15
+	Hs
		484083 CALM3_HUMAN (80-147): 4.86e-12: 61.3: 40.58		PP2BC_HUMAN (64-583): 0: 685: 48.15
+	Dd
		361258 CALM_DICDI (72-147): 1.12e-12: 63.3: 37.66		PP2BA_DICDI (20-584): 0: 644: 46.99
+	Hs
		648468 CALL3_HUMAN (85-147): 4.31e-11: 59: 40.63		PP1G_HUMAN (106-423): 1.57e-175: 501: 33.65
+	Hs
		484096 CALM3_HUMAN (80-147): 4.86e-12: 61.3: 40.58		PP1B_HUMAN (92-412): 7.6e-172: 492: 31.92
+	Zm
		11196 A0A1D6FBD8_MAIZE (12-73): 9.51e-11: 57.4: 50.00		B4FJL0_MAIZE (106-412): 1.13e-172: 494: 37.46
+	Hs
		648486 CALL3_HUMAN (85-147): 4.31e-11: 59: 40.63		PP1B_HUMAN (92-412): 7.6e-172: 492: 31.92
+	Pf
		907226 CALM_PLAF7 (80-147): 6.22e-11: 58.3: 40.58		Q8IAM8_PLAF7 (452-573): 5.53e-20: 95.9: 26.83