HitPredict

Interactor 1: CALM (P06787)
Calmodulin (CaM)
Gene: CMD1

Interactor 2: MYO4 (P32492)
Myosin-4 (SWI5-dependent HO expression protein 1)
Gene: MYO4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.870

Property	Details
Experiments	11474067, 11805837, 37968396
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	EF-hand_7~IQ, EF-hand_7~Myosin_head
Common GO terms	GO:0005933 - cellular bud GO:0005934 - cellular bud tip GO:0030050 - vesicle transport along actin filament GO:0031475 - myosin V complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 147 Sc			1 1471
+	Sc
		420223 CALM_YEAST (1-147): 4.58e-47: 151: 100.00		MYO2_YEAST (1-1428): 0: 1103: 48.58
+	Sp
		293469 CALM_SCHPO (73-147): 2.57e-11: 59.4: 35.53		MYO52_SCHPO (2-1448): 0: 985: 35.72
+	Sp
		251969 CALM_SCHPO (73-147): 2.57e-11: 59.4: 35.53		MYO51_SCHPO (3-1423): 0: 962: 32.07
+	Dm
		906697 CALM_DROME (80-147): 7.11e-12: 61: 40.58		MYO7A_DROME (1-966): 0: 932: 32.89
+	Hs
		484202 CALM3_HUMAN (80-147): 4.86e-12: 61.3: 40.58		MYO10_HUMAN (3-1001): 0: 930: 31.07
+	Hs
		648611 CALL3_HUMAN (85-147): 4.31e-11: 59: 40.63		MYO10_HUMAN (3-1001): 0: 930: 31.07
+	Dm
		51918 CALL_DROME (11-76): 3.67e-17: 74.6: 37.88		A1Z6Z9_DROME (1-1444): 0: 895: 30.18
+	Dm
		51921 CALM_DROME (80-147): 7.11e-12: 61: 40.58		A1Z6Z9_DROME (1-1444): 0: 895: 30.18
+	Hs
		484206 CALM3_HUMAN (80-147): 4.86e-12: 61.3: 40.58		MYO5C_HUMAN (703-1435): 1.32e-47: 189: 12.71
+	Hs
		484218 CALM3_HUMAN (80-147): 4.86e-12: 61.3: 40.58		MYO5B_HUMAN (704-1435): 3.48e-42: 172: 11.71
+	Hs
		648467 CALL3_HUMAN (85-147): 4.31e-11: 59: 40.63		MYH9_HUMAN (798-1108): 8.36e-09: 62.7: 12.18