HitPredict

Interactor 1: RAD3 (P06839)
General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (DNA repair helicase RAD3) (RNA polymerase II transcription factor B subunit RAD3) (TFB subunit RAD3)
Gene: RAD3

Interactor 2: RAD25 (Q00578)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2 (TFIIH subunit XPB/SSL2) (EC 5.6.2.4) (DNA 3'-5' helicase/translocase XPB/SSL2) (DNA repair helicase RAD25/SSL2) (RNA polymerase II transcription factor B subunit SSL2) (TFB subunit SSL2) (Suppressor of stem-loop mutation 2)
Gene: SSL2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.751

The method score is based on:

Property Details
Experiments 8171014, 26340423, 8557668, 7961739, 7768886, 8631896, 8621533, 33453189, 36041630, 37968396
Identification Methods coimmunoprecipitation, pull down, biochemical, affinity chromatography technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000019 - regulation of mitotic recombination
GO:0000112 - nucleotide-excision repair factor 3 complex
GO:0000439 - transcription factor TFIIH core complex
GO:0003678 - DNA helicase activity
GO:0005524 - ATP binding
and 7 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 778
Sc

1 843
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024