HitPredict

Interactor 1: H2B1J (P06899)
Histone H2B type 1-J (Histone H2B.1) (Histone H2B.r) (H2B/r)
Gene: H2BC11

Interactor 2: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 491
+	Hs
		241505 H2B1K_HUMAN (1-126): 1.26e-53: 166: 99.21		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		918295 H2B1C_HUMAN (1-126): 1.04e-53: 166: 98.41		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		962807 H2B2E_HUMAN (1-126): 5.68e-54: 166: 99.21		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		962859 H2B3B_HUMAN (1-126): 8.4e-52: 161: 95.24		MDM2_HUMAN (1-491): 0: 710: 100.00