Interactor 1: HIS7 (P06987)
Histidine biosynthesis bifunctional protein HisB [Includes: Histidinol-phosphatase (EC 3.1.3.15); Imidazoleglycerol-phosphate dehydratase (IGPD) (EC 4.2.1.19)]
Gene: hisB
Interactor 2: HIS7 (P06987)
Histidine biosynthesis bifunctional protein HisB [Includes: Histidinol-phosphatase (EC 3.1.3.15); Imidazoleglycerol-phosphate dehydratase (IGPD) (EC 4.2.1.19)]
Gene: hisB
Species: Escherichia coli K-12
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.58 | 1.00 | 0.764 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24561554 |
| Identification Methods | two hybrid, affinity chromatography technology, two hybrid array, pull down, luminescence based mammalian interactome mapping |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Hydrolase_like~Hydrolase_like, IGPD~IGPD |
| Common GO terms | GO:0000105 - L-histidine biosynthetic process GO:0004401 - histidinol-phosphatase activity GO:0004424 - imidazoleglycerol-phosphate dehydratase activity GO:0005737 - cytoplasm GO:0046872 - metal ion binding |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
