HitPredict

Interactor 1: POXB (P07003)
Pyruvate dehydrogenase [ubiquinone] (EC 1.2.5.1) (Pyruvate oxidase) (POX) (Pyruvate:ubiquinone-8 oxidoreductase)
Gene: POXB

Interactor 2: POXB (P07003)
Pyruvate dehydrogenase [ubiquinone] (EC 1.2.5.1) (Pyruvate oxidase) (POX) (Pyruvate:ubiquinone-8 oxidoreductase)
Gene: POXB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 18988747, 16858726
Identification Methods x-ray crystallography, molecular sieving, blue native page
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TPP_enzyme_C~TPP_enzyme_C, TPP_enzyme_C~TPP_enzyme_M, TPP_enzyme_C~TPP_enzyme_N, TPP_enzyme_M~TPP_enzyme_M, TPP_enzyme_M~TPP_enzyme_N, TPP_enzyme_N~TPP_enzyme_N
Common GO terms GO:0000287 - magnesium ion binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006090 - pyruvate metabolic process
GO:0008289 - lipid binding
and 6 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 572
Ec

1 572
+ At
+ Ec
+ Ec
+ Sc
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Nc
+ Sp
+ Sc
+ Zm
+ Ec
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024