HitPredict

Interactor 1: SDHB (P07014)
Succinate dehydrogenase iron-sulfur subunit (EC 1.3.5.1)
Gene: SDHB

Interactor 2: SDHA (P0AC41)
Succinate dehydrogenase flavoprotein subunit (EC 1.3.5.1)
Gene: SDHA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.850

The method score is based on:

Property Details
Experiments 24561554, 12560550, 16079137
Identification Methods two hybrid, x-ray crystallography, blue native page, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FAD_binding_2~Fer2_3, Fer2_3~Succ_DH_flav_C, FAD_binding_2~Fer4_17
Common GO terms GO:0005886 - plasma membrane
GO:0006099 - tricarboxylic acid cycle
GO:0008177 - succinate dehydrogenase (quinone) activity
GO:0009055 - electron transfer activity
GO:0009060 - aerobic respiration
and 2 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 238
Ec

1 588
+ Hs
+ Sc
+ Sc
+ Hp
+ Ec
+ Nv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024