Interactor 1: TY3H (P07101)
Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH)
Gene: TH

Interactor 2: TY3H (P07101)
Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH)
Gene: TH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.794

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, mammalian protein protein interaction trap
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Biopterin_H~Biopterin_H
Common GO terms GO:0001666 - response to hypoxia
GO:0001963 - synaptic transmission, dopaminergic
GO:0001975 - response to amphetamine
GO:0003007 - heart morphogenesis
GO:0004511 - tyrosine 3-monooxygenase activity
and 74 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 528
Hs

1 528
+ Hs
+ Hs
+ Dd

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Last updated: 15 Jul 2024