Interactor 1: TYRP1 (P07147)
5,6-dihydroxyindole-2-carboxylic acid oxidase (DHICA oxidase) (EC 1.14.18.-) (Brown locus protein) (Catalase B) (Tyrosinase-related protein 1) (TRP) (TRP-1) (TRP1)
Gene: TYRP1

Interactor 2: TYRO (P11344)
Tyrosinase (EC 1.14.18.1) (Albino locus protein) (Monophenol monooxygenase)
Gene: Tyr

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 18042623, 9918801
Identification Methods cross-linking study, molecular sieving, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Tyrosinase~Tyrosinase
Common GO terms GO:0004503 - tyrosinase activity
GO:0033162 - melanosome membrane
GO:0042470 - melanosome
GO:0042803 - protein homodimerization activity
GO:0043473 - pigmentation
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 537
Mm

1 533
+ Mm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024