Interactor 1: FAS1 (P07149)
Fatty acid synthase subunit beta (EC 2.3.1.86) [Includes: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9); [Acyl-carrier-protein] acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] malonyltransferase (EC 2.3.1.39); S-acyl fatty acid synthase thioesterase (EC 3.1.2.14)]
Gene: FAS1
Interactor 2: FAS2 (P19097)
Fatty acid synthase subunit alpha (EC 2.3.1.86) [Includes: Acyl carrier; 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) (Beta-ketoacyl reductase); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41) (Beta-ketoacyl synthase)]
Gene: FAS2
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.967 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8910467, 18725634, 20231485, 16554755, 37968396, 37949058, 350874, 17431182 |
| Identification Methods | biophysical, cosedimentation in solution, x-ray crystallography, 3D electron microscopy, x ray scattering, affinity chromatography technology, electron microscopy, chromatography technology, tandem affinity purification |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SAT~ketoacyl-synt, Ketoacyl-synt_C~SAT |
| Common GO terms | GO:0004312 - fatty acid synthase activity GO:0004321 - fatty-acyl-CoA synthase activity GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0005835 - fatty acid synthase complex and 1 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
