Interactor 1: TNR16 (P07174)
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)
Gene: Ngfr

Interactor 2: TNR16 (P07174)
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)
Gene: Ngfr

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 18596692, 11756426
Identification Methods cosedimentation in solution, cross-linking study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death, TNFR_16_TM~TNFR_16_TM, TNFR_c6~TNFR_c6
Common GO terms GO:0001540 - amyloid-beta binding
GO:0001678 - intracellular glucose homeostasis
GO:0001942 - hair follicle development
GO:0005035 - death receptor activity
GO:0005168 - neurotrophin TRKA receptor binding
and 73 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 425
Rn

1 425
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
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+ Hs
+ Hs
+ Hs
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+ Hs

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Last updated: 15 Jul 2024