Interactor 1: NFL (P07196)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: NEFL

Interactor 2: GFAP (P14136)
Glial fibrillary acidic protein (GFAP)
Gene: GFAP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 26871637, 32296183, 33961781, unassigned1304, 32814053
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid pooling approach, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005882 - intermediate filament
GO:0045109 - intermediate filament organization
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 543
Hs

1 432
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024