HitPredict

Interactor 1: NFL (P07196)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: NEFL

Interactor 2: KIFC3 (Q9BVG8)
Kinesin-like protein KIFC3
Gene: KIFC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.559

Property	Details
Experiments	25416956, 26871637
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 833
+	Hs
		965454 K22O_HUMAN (69-414): 1.55e-134: 406: 32.09		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		409216 K2C8_HUMAN (69-431): 4.2e-132: 394: 36.44		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		443768 VIME_HUMAN (34-402): 6.74e-84: 270: 49.59		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		318875 K2C75_HUMAN (2-411): 2.04e-77: 255: 28.40		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		535548 GFAP_HUMAN (66-401): 1.36e-70: 234: 48.21		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		781976 PERI_HUMAN (9-401): 1.77e-69: 232: 48.12		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		1055194 K1H2_HUMAN (6-407): 7.45e-68: 227: 23.57		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		1270302 KRT35_HUMAN (2-400): 1.46e-67: 227: 26.43		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		531623 K2C5_HUMAN (56-403): 3.13e-64: 221: 31.62		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		380515 K2C6B_HUMAN (56-419): 8.8e-64: 220: 30.79		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		821683 K2C6C_HUMAN (56-416): 1.35e-63: 219: 31.04		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		359529 K2C6A_HUMAN (56-419): 5.65e-62: 215: 31.06		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		111194 I6L9F6_HUMAN (219-376): 2.5e-29: 119: 61.01		KIFC3_HUMAN (1-833): 0: 543: 100.00
+	Hs
		231468 PERI_HUMAN (9-401): 1.77e-69: 232: 48.12		KIF1B_HUMAN (451-800): 4.85e-114: 384: 31.75
+	Hs
		111158 I6L9F6_HUMAN (219-376): 2.5e-29: 119: 61.01		KIF1B_HUMAN (451-800): 4.85e-114: 384: 31.75
+	Hs
		99725 K2C6A_HUMAN (56-419): 5.65e-62: 215: 31.06		F5H3M2_HUMAN (50-364): 2.62e-10: 66.3: 12.69