HitPredict

Interactor 1: NFL (P07196)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: NEFL

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 914
+	Hs
		1081760 AINX_HUMAN (66-401): 1.66e-91: 290: 58.11		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		443814 VIME_HUMAN (34-402): 6.74e-84: 270: 49.59		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		569124 DESM_HUMAN (69-402): 4.31e-72: 239: 53.89		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		535572 GFAP_HUMAN (66-401): 1.36e-70: 234: 48.21		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		781989 PERI_HUMAN (9-401): 1.77e-69: 232: 48.12		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		422263 NFL_HUMAN (1-543): 1.42e-151: 446: 100.00		FGD4_HUMAN (312-858): 1.12e-81: 281: 18.53
+	Hs
		422187 NFL_HUMAN (1-543): 1.42e-151: 446: 100.00		ITSN1_HUMAN (402-782): 1.02e-76: 276: 18.14
+	Hs
		422237 NFL_HUMAN (1-543): 1.42e-151: 446: 100.00		NGEF_HUMAN (354-827): 7.02e-77: 267: 17.15
+	Hs
		422224 NFL_HUMAN (1-543): 1.42e-151: 446: 100.00		ARHGJ_HUMAN (378-821): 6.57e-75: 264: 18.90
+	Hs
		409257 K2C8_HUMAN (69-431): 4.2e-132: 394: 36.44		ARHGC_HUMAN (316-874): 1.5e-78: 281: 16.35
+	Hs
		409270 K2C8_HUMAN (69-431): 4.2e-132: 394: 36.44		PKHG1_HUMAN (367-887): 3.48e-78: 280: 16.79
+	Hs
		957982 AINX_HUMAN (66-401): 1.66e-91: 290: 58.11		FGD1_HUMAN (353-836): 1.48e-74: 265: 19.60
+	Hs
		1081729 AINX_HUMAN (66-401): 1.66e-91: 290: 58.11		ARHGJ_HUMAN (378-821): 6.57e-75: 264: 18.90
+	Hs
		422165 NFL_HUMAN (1-543): 1.42e-151: 446: 100.00		ECT2L_HUMAN (453-721): 2.8e-23: 108: 28.93
+	Hs
		443876 VIME_HUMAN (34-402): 6.74e-84: 270: 49.59		PKHG1_HUMAN (367-887): 3.48e-78: 280: 16.79
+	Hs
		422404 NFM_HUMAN (82-409): 4.21e-72: 249: 54.71		ITSN1_HUMAN (402-782): 1.02e-76: 276: 18.14
+	Hs
		569085 DESM_HUMAN (69-402): 4.31e-72: 239: 53.89		ITSN1_HUMAN (402-782): 1.02e-76: 276: 18.14
+	Hs
		535403 GFAP_HUMAN (66-401): 1.36e-70: 234: 48.21		ITSN1_HUMAN (402-782): 1.02e-76: 276: 18.14
+	Hs
		962562 AINX_HUMAN (66-401): 1.66e-91: 290: 58.11		ECT2L_HUMAN (453-721): 2.8e-23: 108: 28.93
+	Hs
		167087 AINX_HUMAN (66-401): 1.66e-91: 290: 58.11		ARHGB_HUMAN (453-651): 2.54e-12: 73.2: 23.53