HitPredict

Interactor 1: NFM (P07197)
Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein)
Gene: NEFM

Interactor 2: CAN1 (P07384)
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)
Gene: CAPN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 916 Hs			1 714
+	Hs
		427896 AINX_HUMAN (8-494): 2.98e-91: 300: 47.69		CAN1_HUMAN (1-714): 0: 950: 100.00
+	Hs
		427831 VIME_HUMAN (8-413): 1.85e-77: 261: 44.61		CAN1_HUMAN (1-714): 0: 950: 100.00
+	Hs
		427839 DESM_HUMAN (93-413): 5.49e-63: 222: 45.79		CAN1_HUMAN (1-714): 0: 950: 100.00
+	Hs
		1081727 AINX_HUMAN (8-494): 2.98e-91: 300: 47.69		CAN12_HUMAN (23-714): 0: 724: 41.56
+	Hs
		443283 VIME_HUMAN (8-413): 1.85e-77: 261: 44.61		CALM3_HUMAN (532-617): 5.54e-14: 71.6: 20.69
+	Hs
		659617 MYH9_HUMAN (52-696): 1.41e-23: 109: 11.28		GRAN_HUMAN (534-712): 5.09e-64: 213: 30.17
+	Hs
		422330 NFM_HUMAN (1-916): 4.85e-65: 237: 100.00		CALM3_HUMAN (532-617): 5.54e-14: 71.6: 20.69