HitPredict

Interactor 1: NFM (P07197)
Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein)
Gene: NEFM

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 916 Hs			1 793
+	Hs
		443471 VIME_HUMAN (8-413): 1.85e-77: 261: 44.61		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		531529 K2C5_HUMAN (67-411): 7.57e-92: 304: 29.60		DESP_HUMAN (13-640): 3.03e-22: 105: 14.35
+	Hs
		359462 K2C6A_HUMAN (67-411): 1.14e-91: 303: 30.46		DESP_HUMAN (13-640): 3.03e-22: 105: 14.35
+	Hs
		821662 K2C6C_HUMAN (6-411): 3.81e-93: 307: 27.58		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Hs
		1068542 AINX_HUMAN (8-494): 2.98e-91: 300: 47.69		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Hs
		148869 AINX_HUMAN (8-494): 2.98e-91: 300: 47.69		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		422187 NFL_HUMAN (74-420): 2.2e-73: 253: 53.16		ITSN1_HUMAN (235-636): 6.18e-27: 120: 21.34
+	Mm
		589621 VIME_MOUSE (58-413): 4.53e-76: 258: 47.75		ROCK2_MOUSE (1-688): 4.34e-24: 111: 11.48
+	Hs
		443305 VIME_HUMAN (8-413): 1.85e-77: 261: 44.61		DESP_HUMAN (13-640): 3.03e-22: 105: 14.35
+	Mm
		93542 NFL_MOUSE (74-420): 1.88e-75: 258: 53.16		DESP_MOUSE (13-637): 1.8e-22: 105: 13.96
+	Hs
		422356 NFM_HUMAN (1-916): 4.85e-65: 237: 100.00		MYH10_HUMAN (55-788): 1.22e-26: 119: 10.63
+	Hs
		234175 VIME_HUMAN (8-413): 1.85e-77: 261: 44.61		PEPL_HUMAN (15-671): 2.36e-17: 89.5: 8.61
+	Hs
		443532 VIME_HUMAN (8-413): 1.85e-77: 261: 44.61		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Hs
		148307 VIME_HUMAN (8-413): 1.85e-77: 261: 44.61		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		422342 NFM_HUMAN (1-916): 4.85e-65: 237: 100.00		DESP_HUMAN (13-640): 3.03e-22: 105: 14.35
+	Hs
		422355 NFM_HUMAN (1-916): 4.85e-65: 237: 100.00		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		148291 NFL_HUMAN (74-420): 2.2e-73: 253: 53.16		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Mm
		589655 VIME_MOUSE (58-413): 4.53e-76: 258: 47.75		PEPL_MOUSE (27-700): 2.01e-12: 73.3: 10.60
+	Hs
		422398 NFM_HUMAN (1-916): 4.85e-65: 237: 100.00		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Hs
		148292 NFM_HUMAN (1-916): 4.85e-65: 237: 100.00		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87