HitPredict

Interactor 1: NOTCH (P07207)
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]
Gene: N

Interactor 2: LAMC1 (P15215)
Laminin subunit gamma-1 (Laminin B2 chain)
Gene: LanB2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25294943
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007411 - axon guidance
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2703 Dm			1 1639
+	Dm
		422709 NOTCH_DROME (51-2703): 0: 1437: 100.00		NOTCH_DROME (862-1159): 1.92e-16: 88: 14.68
+	Dm
		422742 NOTCH_DROME (51-2703): 0: 1437: 100.00		LAMA_DROME (260-419): 1.16e-09: 65.7: 20.86
+	Hs
		804372 NOTC3_HUMAN (1-1339): 2.72e-175: 601: 31.98		NOTC1_HUMAN (552-1156): 6.2e-61: 234: 14.24
+	Hs
		1357250 NOTC3_HUMAN (1-1339): 2.72e-175: 601: 31.98		NOTC3_HUMAN (258-740): 2.22e-31: 137: 10.90
+	Hs
		804163 NOTC1_HUMAN (1-1067): 5.28e-140: 493: 32.24		NOTC1_HUMAN (552-1156): 6.2e-61: 234: 14.24
+	Hs
		980576 NOTC3_HUMAN (1-1339): 2.72e-175: 601: 31.98		NOTC2_HUMAN (248-561): 4.79e-16: 86.9: 14.29
+	Dm
		65546 A8JNM5_DROME (1581-2488): 2.08e-148: 522: 14.49		NOTCH_DROME (862-1159): 1.92e-16: 88: 14.68
+	Hs
		804293 ANR44_HUMAN (1645-2307): 1.87e-108: 375: 12.98		NOTC1_HUMAN (552-1156): 6.2e-61: 234: 14.24
+	Hs
		804213 NOTC1_HUMAN (1-1067): 5.28e-140: 493: 32.24		NOTC2_HUMAN (248-561): 4.79e-16: 86.9: 14.29
+	Hs
		1237561 ANR44_HUMAN (1645-2307): 1.87e-108: 375: 12.98		NOTC3_HUMAN (258-740): 2.22e-31: 137: 10.90
+	Hs
		980449 ANR44_HUMAN (1645-2307): 1.87e-108: 375: 12.98		NOTC2_HUMAN (248-561): 4.79e-16: 86.9: 14.29
+	Hs
		804379 JAG2_HUMAN (9-347): 1.83e-38: 160: 26.02		NOTC1_HUMAN (552-1156): 6.2e-61: 234: 14.24
+	Hs
		724367 FBN2_HUMAN (25-1664): 3.34e-78: 292: 19.66		NOTC2_HUMAN (248-561): 4.79e-16: 86.9: 14.29
+	Hs
		804198 JAG1_HUMAN (3-353): 2.79e-31: 137: 25.78		NOTC1_HUMAN (552-1156): 6.2e-61: 234: 14.24
+	Dm
		90684 E1JHA6_DROME (1047-1721): 6.75e-59: 229: 18.73		NOTCH_DROME (862-1159): 1.92e-16: 88: 14.68
+	Hs
		1357251 JAG2_HUMAN (9-347): 1.83e-38: 160: 26.02		NOTC3_HUMAN (258-740): 2.22e-31: 137: 10.90
+	Hs
		944134 JAG1_HUMAN (3-353): 2.79e-31: 137: 25.78		NOTC3_HUMAN (258-740): 2.22e-31: 137: 10.90
+	Hs
		980578 JAG2_HUMAN (9-347): 1.83e-38: 160: 26.02		NOTC2_HUMAN (248-561): 4.79e-16: 86.9: 14.29
+	Hs
		944119 JAG1_HUMAN (3-353): 2.79e-31: 137: 25.78		NOTC2_HUMAN (248-561): 4.79e-16: 86.9: 14.29