Interactor 1: NOTCH (P07207)
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]
Gene: N

Interactor 2: SUH (P28159)
Suppressor of hairless protein (J kappa-recombination signal-binding protein) (RBP-J kappa)
Gene: Su(H)

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 11390662, 15123610, 10898989, 25588307, 9851979, 29030483, 29478922, 17545467, 15704125, 25650119, 27404588, 21737682, 22125648, 23840889, 25280943, 7954795, 8755476, 28928428, 25452105, 15668164 and 6 others

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Identification Methods affinity chromatography technology, two hybrid, pull down, cosedimentation in solution, transmission electron microscopy, isothermal titration calorimetry, molecular sieving, anti tag coimmunoprecipitation, experimental interaction detection
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~BTD, Ank_2~LAG1-DNAbind, Ank_2~TIG_SUH
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0007219 - Notch signaling pathway
GO:0007480 - imaginal disc-derived leg morphogenesis
and 11 others

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Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 2703
Dm

1 594
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024