HitPredict

Interactor 1: TOM70 (P07213)
Mitochondrial import receptor subunit TOM70 (70 kDa mitochondrial outer membrane protein) (Translocase of outer membrane 70 kDa subunit)
Gene: TOM70

Interactor 2: HSP71 (P10591)
Heat shock protein SSA1 (Heat shock protein YG100)
Gene: SSA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	27412066, 35876647, 22940862, 19536198, 16429126
Identification Methods	pull down, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006626 - protein targeting to mitochondrion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 617 Sc			1 642
+	Sc
		422981 TOM70_YEAST (1-617): 5.7e-92: 298: 100.00		HSP72_YEAST (1-642): 0: 922: 96.26
+	Sc
		491161 TOM71_YEAST (4-617): 1e-81: 271: 47.75		HSP71_YEAST (1-642): 0: 925: 100.00
+	Sc
		493919 TOM71_YEAST (4-617): 1e-81: 271: 47.75		HSP72_YEAST (1-642): 0: 922: 96.26
+	Hs
		564043 PPP5_HUMAN (86-204): 1.12e-38: 151: 32.23		HSP76_HUMAN (4-642): 0: 940: 69.94
+	Mm
		926131 PPP5_MOUSE (85-267): 5.98e-40: 154: 22.87		HSP7C_MOUSE (2-642): 0: 937: 74.07
+	Hs
		503738 PPP5_HUMAN (86-204): 1.12e-38: 151: 32.23		HSP7C_HUMAN (2-642): 0: 937: 73.91
+	At
		612321 OE64C_ARATH (71-214): 7.24e-26: 114: 29.45		HS701_ARATH (2-642): 0: 939: 71.25
+	At
		1338008 HSOP1_ARATH (18-235): 9.92e-23: 104: 19.18		HS704_ARATH (2-642): 0: 941: 71.10
+	Hs
		684439 STIP1_HUMAN (42-274): 3.32e-18: 90.2: 17.09		HS71L_HUMAN (2-642): 0: 949: 72.52
+	Hs
		297027 TOM70_HUMAN (164-605): 1.05e-20: 98.3: 11.63		HSP7C_HUMAN (2-642): 0: 937: 73.91
+	Sc
		549702 STI1_YEAST (40-401): 1.41e-12: 72.4: 13.71		HSP74_YEAST (1-642): 0: 961: 81.09
+	Hs
		564017 STIP1_HUMAN (42-274): 3.32e-18: 90.2: 17.09		HSP76_HUMAN (4-642): 0: 940: 69.94
+	Hs
		174578 OGT1_HUMAN (17-311): 4.88e-18: 90.6: 8.70		HSP7C_HUMAN (2-642): 0: 937: 73.91
+	Hs
		503534 STIP1_HUMAN (42-274): 3.32e-18: 90.2: 17.09		HSP7C_HUMAN (2-642): 0: 937: 73.91
+	Hs
		483776 STIP1_HUMAN (42-274): 3.32e-18: 90.2: 17.09		HS71B_HUMAN (2-642): 0: 929: 73.76
+	Hs
		684557 STIP1_HUMAN (42-274): 3.32e-18: 90.2: 17.09		HSP72_HUMAN (2-642): 0: 923: 71.05
+	Hs
		503512 CDC27_HUMAN (92-371): 1.75e-11: 69.4: 10.80		HSP7C_HUMAN (2-642): 0: 937: 73.91
+	Sc
		449890 STI1_YEAST (40-401): 1.41e-12: 72.4: 13.71		HSP73_YEAST (1-642): 0: 925: 79.05
+	Sc
		490225 STI1_YEAST (40-401): 1.41e-12: 72.4: 13.71		HSP71_YEAST (1-642): 0: 925: 100.00
+	Sc
		493107 STI1_YEAST (40-401): 1.41e-12: 72.4: 13.71		HSP72_YEAST (1-642): 0: 922: 96.26