HitPredict

Interactor 1: PROS (P07225)
Vitamin K-dependent protein S
Gene: PROS1

Interactor 2: EDN3 (P14138)
Endothelin-3 (ET-3) (Preproendothelin-3) (PPET3)
Gene: EDN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 676 Hs			1 238
+	Hs
		129684 AGRIN_HUMAN (247-463): 6.35e-23: 106: 16.59		EDN3_HUMAN (1-238): 3.65e-155: 431: 100.00
+	Hs
		535637 GAS6_HUMAN (3-163): 9.98e-17: 86.1: 15.53		EDN3_HUMAN (1-238): 3.65e-155: 431: 100.00
+	Hs
		172641 LAMA5_HUMAN (59-325): 1.33e-10: 67.3: 10.85		EDN3_HUMAN (1-238): 3.65e-155: 431: 100.00
+	Hs
		535684 CELR1_HUMAN (237-379): 4.59e-09: 62.2: 8.73		EDN3_HUMAN (1-238): 3.65e-155: 431: 100.00