Interactor 1: PDIA1 (P07237)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55)
Gene: P4HB

Interactor 2: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 33957083
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment
GO:0005829 - cytosol
GO:0005925 - focal adhesion
and 7 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 508
Hs

1 654
+ Hs
+ Hs
+ Hs
+ Nc
+ Sc
+ Sc
+ Mm
+ Mm
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Hs
+ At
+ Nc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024