HitPredict

Interactor 1: PDIA1 (P07237)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55)
Gene: P4HB

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26618866, 29924966
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019899 - enzyme binding GO:0032991 - protein-containing complex GO:0034976 - response to endoplasmic reticulum stress
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 508 Hs			1 1480
+	Hs
		528620 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528451 PDIA4_HUMAN (330-505): 3.94e-23: 104: 22.22		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529648 ERP44_HUMAN (363-494): 1.8e-23: 104: 17.39		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529142 PDIA6_HUMAN (372-462): 5.71e-09: 60.1: 36.26		CFTR_HUMAN (1-1480): 0: 1031: 100.00