Interactor 1: PDIA1 (P07237)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55)
Gene: P4HB

Interactor 2: MTP (P55157)
Microsomal triglyceride transfer protein large subunit
Gene: MTTP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23475612
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MTP_lip_bd~Thioredoxin, Thioredoxin~Vitellogenin_N, MTP_lip_bd~Thioredoxin_6
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0005829 - cytosol
GO:0046982 - protein heterodimerization activity
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 508
Hs

1 894
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024