Interactor 1: PDIA1 (P07237)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55)
Gene: P4HB

Interactor 2: DJC10 (Q8IXB1)
DnaJ homolog subfamily C member 10 (EC 1.8.4.-) (Endoplasmic reticulum DNA J domain-containing protein 5) (ER-resident protein ERdj5) (ERdj5) (Macrothioredoxin) (MTHr)
Gene: DNAJC10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 33957083
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DnaJ~Thioredoxin, Thioredoxin~Thioredoxin, Thioredoxin~Thioredoxin_6
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0015035 - protein-disulfide reductase activity
GO:0034663 - endoplasmic reticulum chaperone complex
GO:0034975 - protein folding in endoplasmic reticulum
and 1 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 508
Hs

1 793
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Ce
+ Hs
+ Nc
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024