HitPredict

Interactor 1: PDIA1 (P07237)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55)
Gene: P4HB

Interactor 2: DJC16 (Q9Y2G8)
DnaJ homolog subfamily C member 16 (Endoplasmic reticulum DNA J domain-containing protein 8) (ER-resident protein ERdj8) (ERdj8)
Gene: DNAJC16

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~Thioredoxin, Thioredoxin~Thioredoxin, Thioredoxin~Thioredoxin_6
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 508 Hs			1 782
+	Hs
		671964 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		DJC16_HUMAN (1-782): 0: 955: 100.00
+	Mm
		447645 PDIA1_MOUSE (15-508): 4.41e-150: 440: 94.33		ERP44_MOUSE (148-504): 5.73e-50: 182: 12.60
+	Hs
		423380 PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00		DJB11_HUMAN (7-232): 6.1e-36: 141: 26.38
+	Hs
		423372 PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00		DJB12_HUMAN (28-160): 6.64e-35: 138: 32.33
+	Hs
		423379 PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00		DNJB9_HUMAN (9-152): 2.73e-36: 138: 34.72
+	Mm
		653446 PDIA3_MOUSE (4-495): 1.94e-119: 362: 31.69		ERP44_MOUSE (148-504): 5.73e-50: 182: 12.60
+	Hs
		423107 PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00		PDIA1_HUMAN (80-244): 3.2e-12: 71.9: 14.79
+	Hs
		423286 PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00		DJC10_HUMAN (56-248): 2.28e-11: 69.6: 12.00
+	Dm
		870429 Q3YMU0_DROME (2-491): 6.16e-107: 329: 31.80		PDI_DROME (158-513): 9.32e-52: 190: 12.10
+	Hs
		423123 PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00		PDIA4_HUMAN (121-245): 6.82e-10: 64.6: 16.92
+	Hs
		671948 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		DJB11_HUMAN (7-232): 6.1e-36: 141: 26.38
+	Hs
		636249 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		DNJB1_HUMAN (26-135): 5.33e-36: 140: 36.04
+	Hs
		671939 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		DJB12_HUMAN (28-160): 6.64e-35: 138: 32.33
+	Hs
		671947 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		DNJB9_HUMAN (9-152): 2.73e-36: 138: 34.72
+	Sc
		572732 PDI_YEAST (21-482): 4.03e-89: 284: 28.15		SCJ1_YEAST (28-333): 2.17e-47: 174: 18.44
+	Sc
		628935 EUG1_YEAST (2-508): 4.03e-84: 271: 21.46		SCJ1_YEAST (28-333): 2.17e-47: 174: 18.44
+	Hs
		671722 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		PDIA3_HUMAN (103-251): 1.3e-11: 70: 13.07
+	Hs
		671862 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		DJC10_HUMAN (56-248): 2.28e-11: 69.6: 12.00
+	Hs
		531739 PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57		PDIA4_HUMAN (121-245): 6.82e-10: 64.6: 16.92
+	Mm
		1265749 PDIA6_MOUSE (349-480): 1.27e-27: 116: 27.27		ERP44_MOUSE (148-504): 5.73e-50: 182: 12.60