Interactor 1: C1TC (P07245)
C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]
Gene: ADE3
Interactor 2: C1TC (P07245)
C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]
Gene: ADE3
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19343713 |
| Identification Methods | biochemical, blue native page |
| Interaction Type | association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FTHFS~FTHFS, THF_DHG_CYH~THF_DHG_CYH, THF_DHG_CYH~THF_DHG_CYH_C, THF_DHG_CYH_C~THF_DHG_CYH_C |
| Common GO terms | GO:0000105 - L-histidine biosynthetic process GO:0004329 - formate-tetrahydrofolate ligase activity GO:0004477 - methenyltetrahydrofolate cyclohydrolase activity GO:0004488 - methylenetetrahydrofolate dehydrogenase (NADP+) activity GO:0005524 - ATP binding and 8 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
