HitPredict

Interactor 1: C1TC (P07245)
C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]
Gene: ADE3

Interactor 2: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	19536198, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 946 Sc			1 613
+	Sc
		450379 C1TM_YEAST (4-946): 0: 1446: 71.10		SSB1_YEAST (1-613): 0: 1128: 100.00
+	Sc
		423528 C1TC_YEAST (1-946): 0: 1447: 100.00		SSB2_YEAST (1-613): 0: 1118: 99.35
+	Sc
		450448 C1TM_YEAST (4-946): 0: 1446: 71.10		SSB2_YEAST (1-613): 0: 1118: 99.35
+	Hs
		503329 C1TC_HUMAN (3-946): 0: 1510: 57.49		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		504269 C1TM_HUMAN (10-946): 0: 1378: 49.73		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Sc
		449867 C1TM_YEAST (4-946): 0: 1446: 71.10		HSP73_YEAST (9-611): 0: 677: 60.66
+	Sc
		512389 MTD1_YEAST (3-298): 2.88e-82: 270: 23.51		SSB1_YEAST (1-613): 0: 1128: 100.00
+	Hs
		503354 MTDC_HUMAN (3-305): 3.45e-119: 369: 38.02		HSP7C_HUMAN (5-612): 0: 900: 59.84