Interactor 1: ARGI1 (P05089)
Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase)
Gene: ARG1
Interactor 2: PD1L1 (Q9NZQ7)
Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (hPD-L1) (B7 homolog 1) (B7-H1) (CD antigen CD274)
Gene: CD274
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.90 | 0.586 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32941674 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Arginase~V-set |
| Common GO terms | GO:0002250 - adaptive immune response GO:0042130 - negative regulation of T cell proliferation GO:0046007 - negative regulation of activated T cell proliferation |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
