HitPredict

Interactor 1: ATPA (P07251)
ATP synthase subunit alpha, mitochondrial
Gene: ATP1

Interactor 2: ATP7 (P30902)
ATP synthase subunit d, mitochondrial
Gene: ATP7

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.906

Property	Details
Experiments	9867807, 37968396, 38551959, 32051233, 22940862
Identification Methods	comigration in non denaturing gel electrophoresis, affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ATP-synt_ab~Mt_ATP-synt_D, ATP-synt_ab_C~Mt_ATP-synt_D
Common GO terms	GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane GO:0005753 - mitochondrial proton-transporting ATP synthase complex GO:0015986 - proton motive force-driven ATP synthesis GO:0046933 - proton-transporting ATP synthase activity, rotational mechanism
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 545 Sc			1 174
+	Hs
		279082 ATPA_HUMAN (11-545): 0: 622: 70.45		ATP5H_HUMAN (1-147): 5.16e-50: 159: 22.45
+	Ce
		1089128 ATPA_CAEEL (11-545): 0: 597: 69.35		Q17763_CAEEL (2-174): 2.03e-50: 162: 14.84
+	Dm
		723127 ATPA_DROME (5-545): 0: 603: 68.82		ATP5H_DROME (1-145): 1.2e-47: 154: 16.55
+	Hs
		279066 ATPB_HUMAN (1-540): 1.58e-173: 502: 22.00		ATP5H_HUMAN (1-147): 5.16e-50: 159: 22.45
+	Sc
		341956 ATPB_YEAST (65-518): 9.6e-152: 446: 24.31		ATP7_YEAST (1-174): 5e-60: 186: 100.00