HitPredict

Interactor 1: PYR1 (P07259)
Multifunctional protein URA2 (Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase) (CPSase-ATCase) [Includes: Glutamine-dependent carbamoyl phosphate synthase (EC 6.3.5.5) (Carbamoyl phosphate synthase P) (CPS-P) (CPSase P) (CPSase-ura) (Pyrimidine-specific carbamoyl phosphate synthase); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (ATCase) (EC 2.1.3.2) (Aspartate transcarbamylase)]
Gene: URA2

Interactor 2: UTP4 (Q06679)
U3 small nucleolar RNA-associated protein 4 (U3 snoRNA-associated protein 4) (U three protein 4) (U3 protein 4 required for transcription) (t-UTP4)
Gene: UTP4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2214 Sc			1 776
+	Hs
		653325 PYR1_HUMAN (21-2212): 0: 2566: 49.18		POC1B_HUMAN (4-168): 2.16e-38: 151: 14.88
+	Sc
		424364 PYR1_YEAST (1-2214): 0: 2535: 100.00		NLE1_YEAST (516-647): 4.72e-13: 74.3: 12.03
+	Hs
		903256 DPYL2_HUMAN (1443-1915): 5.35e-144: 463: 13.38		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		921544 ACACA_HUMAN (382-980): 5.99e-127: 449: 13.35		GBB2_HUMAN (271-595): 3.16e-22: 100: 13.98
+	Hs
		903185 ACACA_HUMAN (382-980): 5.99e-127: 449: 13.35		WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41
+	Hs
		1024070 ACACA_HUMAN (382-980): 5.99e-127: 449: 13.35		SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27