HitPredict

Interactor 1: LEUC (P07264)
3-isopropylmalate dehydratase (EC 4.2.1.33) (Alpha-IPM isomerase) (IPMI) (Isopropylmalate isomerase)
Gene: LEU1

Interactor 2: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31399574, 19536198, 15766533
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 779 Sc			1 705
+	Sc
		365581 LEUC_YEAST (1-779): 0: 978: 100.00		HSP82_YEAST (1-705): 0: 968: 95.63
+	Sc
		543163 ACON_YEAST (8-723): 0: 704: 22.78		HSC82_YEAST (1-705): 0: 977: 100.00
+	Sc
		365761 ACON_YEAST (8-723): 0: 704: 22.78		HSP82_YEAST (1-705): 0: 968: 95.63
+	Sc
		544064 LYS4_YEAST (9-671): 3.42e-156: 472: 23.28		HSC82_YEAST (1-705): 0: 977: 100.00