HitPredict

Interactor 1: KLK3 (P07288)
Prostate-specific antigen (PSA) (EC 3.4.21.77) (Gamma-seminoprotein) (Seminin) (Kallikrein-3) (P-30 antigen) (Semenogelase)
Gene: KLK3

Interactor 2: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 806
+	Hs
		420736 KLK1_HUMAN (1-260): 7.96e-116: 334: 60.54		FGFR3_HUMAN (10-806): 0: 819: 100.00
+	Hs
		428666 TRY1_HUMAN (4-260): 2.96e-114: 329: 40.47		EPHA3_HUMAN (1-786): 0: 641: 20.68
+	Hs
		1072608 TMPS4_HUMAN (7-256): 4.1e-90: 275: 29.77		EPHA7_HUMAN (1-782): 0: 626: 21.22
+	Hs
		872716 TMPS4_HUMAN (7-256): 4.1e-90: 275: 29.77		EPHA4_HUMAN (1-781): 0: 622: 20.78
+	Hs
		409508 HEPS_HUMAN (7-260): 5.01e-97: 292: 32.59		EPHB4_HUMAN (1-786): 8.14e-179: 541: 17.79
+	Hs
		872513 TMPS3_HUMAN (7-259): 6.78e-96: 290: 30.83		EPHB4_HUMAN (1-786): 8.14e-179: 541: 17.79
+	Hs
		872570 TMPSD_HUMAN (7-257): 3.92e-91: 282: 28.95		EPHB4_HUMAN (1-786): 8.14e-179: 541: 17.79
+	Hs
		872582 TMPS4_HUMAN (7-256): 4.1e-90: 275: 29.77		EPHB4_HUMAN (1-786): 8.14e-179: 541: 17.79
+	Hs
		589591 KLK2_HUMAN (1-261): 1.16e-119: 344: 77.01		FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31
+	Hs
		1031173 TMPS4_HUMAN (7-256): 4.1e-90: 275: 29.77		PTK7_HUMAN (5-344): 7.72e-26: 116: 20.47
+	Mm
		372103 CFAD_MOUSE (24-260): 3.06e-37: 133: 35.37		PTK7_MOUSE (160-362): 3.3e-16: 85.6: 17.96