HitPredict

Interactor 1: KLK3 (P07288)
Prostate-specific antigen (PSA) (EC 3.4.21.77) (Gamma-seminoprotein) (Seminin) (Kallikrein-3) (P-30 antigen) (Semenogelase)
Gene: KLK3

Interactor 2: EDEM2 (Q9BV94)
ER degradation-enhancing alpha-mannosidase-like protein 2
Gene: EDEM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 578
+	Hs
		1313602 KLK15_HUMAN (15-260): 1e-96: 285: 39.45		EDEM2_HUMAN (1-578): 0: 817: 100.00
+	Hs
		1313604 TMPS5_HUMAN (8-256): 1.96e-90: 276: 34.22		EDEM2_HUMAN (1-578): 0: 817: 100.00
+	Hs
		409499 HEPS_HUMAN (7-260): 5.01e-97: 292: 32.59		MA1A1_HUMAN (2-484): 0: 620: 27.43
+	Hs
		708163 TMPSD_HUMAN (7-257): 3.92e-91: 282: 28.95		MA1A1_HUMAN (2-484): 0: 620: 27.43
+	Hs
		1318303 KLK15_HUMAN (15-260): 1e-96: 285: 39.45		EDEM3_HUMAN (3-500): 0: 585: 39.19
+	Hs
		1318309 TMPS4_HUMAN (7-256): 4.1e-90: 275: 29.77		EDEM3_HUMAN (3-500): 0: 585: 39.19
+	Hs
		1345089 TMPS4_HUMAN (7-256): 4.1e-90: 275: 29.77		MA1B1_HUMAN (23-482): 0: 545: 29.74
+	Mm
		371607 CFAD_MOUSE (24-260): 3.06e-37: 133: 35.37		MA1A2_MOUSE (4-482): 0: 623: 29.94
+	Mm
		57160 CFAD_MOUSE (24-260): 3.06e-37: 133: 35.37		MA1B1_MOUSE (28-482): 0: 539: 28.60