Interactor 1: CSF1R (P07333)
Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)
Gene: CSF1R

Interactor 2: CSF1R (P07333)
Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)
Gene: CSF1R

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 9380408, 22153499
Identification Methods enzymatic study, x ray scattering
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ig~ig, Ig_3~ig, Ig_3~Ig_3, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0002931 - response to ischemia
GO:0004713 - protein tyrosine kinase activity
GO:0005011 - macrophage colony-stimulating factor receptor activity
GO:0005524 - ATP binding
and 50 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 972
Hs

1 972
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+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024