Interactor 1: CSF1R (P07333)
Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)
Gene: CSF1R
Interactor 2: IL34 (Q6ZMJ4)
Interleukin-34 (IL-34)
Gene: IL34
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.69 | 0.90 | 0.793 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23478061, 22483114 |
| Identification Methods | light scattering, field flow fractionation, x ray scattering, molecular sieving, bio-layer interferometry, isothermal titration calorimetry, transmission electron microscopy, x-ray crystallography |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IL34~ig |
| Common GO terms | GO:0001934 - positive regulation of protein phosphorylation GO:0006954 - inflammatory response GO:0008284 - positive regulation of cell population proliferation GO:0010759 - positive regulation of macrophage chemotaxis GO:0045087 - innate immune response and 3 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
