HitPredict

Interactor 1: CATD (P07339)
Cathepsin D (EC 3.4.23.5) [Cleaved into: Cathepsin D light chain; Cathepsin D heavy chain]
Gene: CTSD

Interactor 2: CCL4 (P13236)
C-C motif chemokine 4 (G-26 T-lymphocyte-secreted protein) (HC21) (Lymphocyte activation gene 1 protein) (LAG-1) (MIP-1-beta(1-69)) (Macrophage inflammatory protein 1-beta) (MIP-1-beta) (PAT 744) (Protein H400) (SIS-gamma) (Small-inducible cytokine A4) (T-cell activation protein 2) (ACT-2) [Cleaved into: MIP-1-beta(3-69)]
Gene: CCL4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12651610
Identification Methods	cleavage assay
Interaction Type	protein cleavage

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 92
+	Hs
		427032 CATD_HUMAN (1-412): 1.41e-171: 487: 100.00		CCL3_HUMAN (1-92): 6.04e-35: 116: 57.61
+	Hs
		134286 CATD_HUMAN (1-412): 1.41e-171: 487: 100.00		CCL21_HUMAN (33-90): 3.63e-17: 72.3: 40.32
+	Hs
		427070 CATD_HUMAN (1-412): 1.41e-171: 487: 100.00		CCL20_HUMAN (3-90): 8.88e-17: 70.4: 30.00