HitPredict

Interactor 1: ANXA2 (P07355)
Annexin A2 (Annexin II) (Annexin-2) (Calpactin I heavy chain) (Calpactin-1 heavy chain) (Chromobindin-8) (Lipocortin II) (Placental anticoagulant protein IV) (PAP-IV) (Protein I) (p36)
Gene: ANXA2

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	35063084, 29636414, 21339331
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 758
+	Hs
		451765 ANXA4_HUMAN (25-339): 5.88e-173: 484: 49.52		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		444818 ANXA5_HUMAN (24-339): 5.27e-160: 451: 46.20		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		376141 ANXA1_HUMAN (1-338): 4.33e-159: 450: 50.72		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		436060 ANXA6_HUMAN (37-337): 1.36e-63: 215: 27.93		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00