HitPredict

Interactor 1: ANXA2 (P07355)
Annexin A2 (Annexin II) (Annexin-2) (Calpactin I heavy chain) (Calpactin-1 heavy chain) (Chromobindin-8) (Lipocortin II) (Placental anticoagulant protein IV) (PAP-IV) (Protein I) (p36)
Gene: ANXA2

Interactor 2: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	20000738
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 143
+	Hs
		451770 ANXA4_HUMAN (25-339): 5.88e-173: 484: 49.52		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Hs
		64111 AXA2L_HUMAN (1-339): 5.8e-170: 477: 97.94		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Hs
		260719 ANXA2_HUMAN (1-339): 3.16e-174: 488: 100.00		H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69
+	Hs
		444827 ANXA5_HUMAN (24-339): 5.27e-160: 451: 46.20		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Hs
		555506 Q6P452_HUMAN (25-339): 4.11e-157: 443: 46.67		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Hs
		3076 A0A0S2Z377_HUMAN (37-337): 1.19e-63: 215: 27.93		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00
+	Hs
		436062 ANXA6_HUMAN (37-337): 1.36e-63: 215: 27.93		H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00