HitPredict

Interactor 1: CO8A (P07357)
Complement component C8 alpha chain (Complement component 8 subunit alpha)
Gene: C8A

Interactor 2: FBX2 (Q9UK22)
F-box only protein 2
Gene: FBXO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 584 Hs			1 296
+	Hs
		1356238 ATS7_HUMAN (340-584): 2.17e-61: 222: 15.77		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1344602 ATS7_HUMAN (340-584): 2.17e-61: 222: 15.77		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		536194 PERF_HUMAN (130-555): 3.29e-60: 211: 18.49		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		1269038 SORL_HUMAN (18-173): 8.18e-34: 139: 18.72		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1269027 SORL_HUMAN (18-173): 8.18e-34: 139: 18.72		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		1224478 UNC5B_HUMAN (501-584): 9.34e-12: 70.2: 34.41		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		957659 LRP2_HUMAN (128-243): 1.52e-10: 66.7: 9.84		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1349415 LRP1B_HUMAN (37-166): 6.97e-09: 61.4: 15.60		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		992712 LRP1_HUMAN (85-253): 1.98e-10: 66.3: 10.33		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81