HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: CATG (P08311)
Cathepsin G (CG) (EC 3.4.21.20) [Cleaved into: Cathepsin G, C-terminal truncated form]
Gene: CTSG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0035578 - azurophil granule lumen and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 255
+	Hs
		428722 TBB3_HUMAN (1-444): 0: 712: 92.57		TRY2_HUMAN (1-246): 9.62e-111: 320: 33.60
+	Hs
		1037334 TBB3_HUMAN (1-444): 0: 712: 92.57		KLK6_HUMAN (1-244): 2.55e-103: 301: 31.86
+	Hs
		1037427 TBB3_HUMAN (1-444): 0: 712: 92.57		KLK11_HUMAN (18-245): 3.22e-98: 290: 32.07
+	Hs
		595528 TBB3_HUMAN (1-444): 0: 712: 92.57		GRAH_HUMAN (1-244): 1.29e-96: 284: 57.55
+	Hs
		428017 TBB5_HUMAN (1-429): 0: 709: 100.00		GRAH_HUMAN (1-244): 1.29e-96: 284: 57.55
+	Hs
		439334 TBB8_HUMAN (1-427): 0: 702: 89.70		CATG_HUMAN (1-255): 1.05e-98: 290: 100.00
+	Hs
		420746 TBB8_HUMAN (1-427): 0: 702: 89.70		KLK1_HUMAN (1-246): 2.45e-97: 287: 32.21
+	Hs
		381216 TBB4A_HUMAN (1-427): 0: 702: 97.42		PRSS8_HUMAN (9-254): 7.58e-96: 286: 30.22
+	Hs
		381123 TBB4A_HUMAN (1-427): 0: 702: 97.42		GRAH_HUMAN (1-244): 1.29e-96: 284: 57.55
+	Hs
		595536 TBB8_HUMAN (1-427): 0: 702: 89.70		GRAH_HUMAN (1-244): 1.29e-96: 284: 57.55
+	Hs
		621370 TBB8_HUMAN (1-427): 0: 702: 89.70		CMA1_HUMAN (13-245): 3.64e-96: 283: 50.64
+	Hs
		1114231 TBB8_HUMAN (1-427): 0: 702: 89.70		KLK15_HUMAN (11-245): 8.15e-95: 280: 33.20
+	Hs
		836354 TBB3_HUMAN (1-444): 0: 712: 92.57		GRAK_HUMAN (20-242): 3.75e-44: 151: 37.55
+	Hs
		428023 TBB5_HUMAN (1-429): 0: 709: 100.00		PRTN3_HUMAN (20-243): 1.73e-41: 144: 37.50
+	Hs
		381126 TBB4A_HUMAN (1-427): 0: 702: 97.42		PRTN3_HUMAN (20-243): 1.73e-41: 144: 37.50
+	Hs
		621789 TBB8_HUMAN (1-427): 0: 702: 89.70		PRTN3_HUMAN (20-243): 1.73e-41: 144: 37.50
+	Mm
		371765 TBB4B_MOUSE (1-427): 0: 707: 98.36		CFAD_MOUSE (5-238): 1.99e-36: 131: 32.93