HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22536447, 25609649
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~Tubulin
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 968
+	Hs
		587560 TBB3_HUMAN (1-444): 0: 712: 92.57		NFKB1_HUMAN (1-968): 0: 796: 100.00
+	Hs
		587517 TBB4B_HUMAN (1-427): 0: 707: 98.36		NFKB1_HUMAN (1-968): 0: 796: 100.00
+	Hs
		2075 A0A0B4J269_HUMAN (19-444): 0: 825: 92.02		TF65_HUMAN (28-420): 6.77e-116: 368: 34.41
+	Hs
		428144 TBB5_HUMAN (1-429): 0: 709: 100.00		RELB_HUMAN (30-459): 1.19e-121: 384: 33.10
+	Hs
		428152 TBB5_HUMAN (1-429): 0: 709: 100.00		TF65_HUMAN (28-420): 6.77e-116: 368: 34.41
+	Hs
		978880 TBB2B_HUMAN (1-430): 0: 707: 97.44		TF65_HUMAN (28-420): 6.77e-116: 368: 34.41
+	Hs
		428154 TBB5_HUMAN (1-429): 0: 709: 100.00		REL_HUMAN (35-484): 6.21e-110: 354: 33.91
+	Hs
		428145 TBB5_HUMAN (1-429): 0: 709: 100.00		ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37
+	Hs
		883508 TBB3_HUMAN (1-444): 0: 712: 92.57		RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00
+	Hs
		428027 TBB5_HUMAN (1-429): 0: 709: 100.00		IKBA_HUMAN (485-767): 1.18e-66: 228: 35.45
+	Hs
		428113 TBB5_HUMAN (1-429): 0: 709: 100.00		RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00
+	Hs
		883476 TBB4B_HUMAN (1-427): 0: 707: 98.36		RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00
+	Hs
		883632 TBB2B_HUMAN (1-430): 0: 707: 97.44		RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00
+	Hs
		121557 TBB5_HUMAN (1-429): 0: 709: 100.00		IKBE_HUMAN (541-751): 2.35e-29: 125: 38.07
+	Hs
		428142 TBB5_HUMAN (1-429): 0: 709: 100.00		NFKB2_HUMAN (701-942): 4.27e-26: 117: 14.23
+	Hs
		961433 TBB2B_HUMAN (1-430): 0: 707: 97.44		NFKB2_HUMAN (701-942): 4.27e-26: 117: 14.23
+	Hs
		428225 TBB5_HUMAN (1-429): 0: 709: 100.00		IKBB_HUMAN (541-743): 4.59e-20: 95.1: 32.39
+	Hs
		1037393 TBB3_HUMAN (1-444): 0: 712: 92.57		Q9H4D1_HUMAN (622-789): 9.95e-18: 90.6: 24.41
+	Hs
		428431 TBB5_HUMAN (1-429): 0: 709: 100.00		Q9H4D1_HUMAN (622-789): 9.95e-18: 90.6: 24.41
+	Hs
		1313672 TBB2B_HUMAN (1-430): 0: 707: 97.44		Q9H4D1_HUMAN (622-789): 9.95e-18: 90.6: 24.41