HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	36470425, 15878338, 19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045121 - membrane raft
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 906
+	Hs
		610390 TBB3_HUMAN (1-444): 0: 712: 92.57		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610348 TBB4B_HUMAN (1-427): 0: 707: 98.36		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610500 TBB2B_HUMAN (1-430): 0: 707: 97.44		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610394 TBB2A_HUMAN (1-430): 0: 704: 96.98		CBL_HUMAN (1-906): 0: 917: 100.00
+	Mm
		610583 TBB5_MOUSE (1-429): 0: 709: 100.00		CBL_MOUSE (1-906): 0: 888: 91.59
+	Mm
		610577 TBB4B_MOUSE (1-427): 0: 707: 98.36		CBL_MOUSE (1-906): 0: 888: 91.59