HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Tubulin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 317
+	Hs
		121557 TBB5_HUMAN (1-429): 0: 709: 100.00		IKBE_HUMAN (3-315): 1.28e-74: 239: 32.10
+	Hs
		428142 TBB5_HUMAN (1-429): 0: 709: 100.00		NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32
+	Hs
		961433 TBB2B_HUMAN (1-430): 0: 707: 97.44		NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32
+	Hs
		862023 TBB4B_HUMAN (1-427): 0: 707: 98.36		DAPK1_HUMAN (27-317): 1.12e-62: 216: 17.11
+	Hs
		428145 TBB5_HUMAN (1-429): 0: 709: 100.00		ANK2_HUMAN (118-315): 9.61e-41: 153: 23.50
+	Hs
		965103 TBB2A_HUMAN (1-430): 0: 704: 96.98		ANK2_HUMAN (118-315): 9.61e-41: 153: 23.50
+	Hs
		883508 TBB3_HUMAN (1-444): 0: 712: 92.57		RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31
+	Hs
		1037393 TBB3_HUMAN (1-444): 0: 712: 92.57		Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31
+	Hs
		428113 TBB5_HUMAN (1-429): 0: 709: 100.00		RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31
+	Hs
		428431 TBB5_HUMAN (1-429): 0: 709: 100.00		Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31
+	Hs
		883476 TBB4B_HUMAN (1-427): 0: 707: 98.36		RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31
+	Hs
		883632 TBB2B_HUMAN (1-430): 0: 707: 97.44		RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31
+	Hs
		1313672 TBB2B_HUMAN (1-430): 0: 707: 97.44		Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31
+	Hs
		933974 TBB4B_HUMAN (1-427): 0: 707: 98.36		Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31
+	Hs
		883510 TBB2A_HUMAN (1-430): 0: 704: 96.98		RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31
+	Hs
		587560 TBB3_HUMAN (1-444): 0: 712: 92.57		NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35
+	Hs
		428013 TBB5_HUMAN (1-429): 0: 709: 100.00		NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35
+	Hs
		587517 TBB4B_HUMAN (1-427): 0: 707: 98.36		NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35
+	Hs
		587570 TBB2A_HUMAN (1-430): 0: 704: 96.98		NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35
+	Hs
		428225 TBB5_HUMAN (1-429): 0: 709: 100.00		IKBB_HUMAN (68-169): 5.17e-13: 70.8: 28.16