HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0032991 - protein-containing complex and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 304
+	Hs
		802589 TBB3_HUMAN (1-444): 0: 712: 92.57		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		802562 TBB4B_HUMAN (1-427): 0: 707: 98.36		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		802593 TBB2A_HUMAN (1-430): 0: 704: 96.98		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		548704 TBB3_HUMAN (1-444): 0: 712: 92.57		VAV_HUMAN (11-189): 6.6e-47: 170: 28.21
+	Hs
		428001 TBB5_HUMAN (1-429): 0: 709: 100.00		VAV_HUMAN (11-189): 6.6e-47: 170: 28.21
+	Hs
		548681 TBB4B_HUMAN (1-427): 0: 707: 98.36		VAV_HUMAN (11-189): 6.6e-47: 170: 28.21
+	Hs
		381112 TBB4A_HUMAN (1-427): 0: 702: 97.42		VAV_HUMAN (11-189): 6.6e-47: 170: 28.21
+	Hs
		924548 TBB3_HUMAN (1-444): 0: 712: 92.57		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		428131 TBB5_HUMAN (1-429): 0: 709: 100.00		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		924460 TBB4B_HUMAN (1-427): 0: 707: 98.36		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		924836 TBB6_HUMAN (1-432): 0: 703: 92.13		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67