HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: MP2K3 (P46734)
Dual specificity mitogen-activated protein kinase kinase 3 (MAP kinase kinase 3) (MAPKK 3) (EC 2.7.12.2) (MAPK/ERK kinase 3) (MEK 3) (Stress-activated protein kinase kinase 2) (SAPK kinase 2) (SAPKK-2) (SAPKK2)
Gene: MAP2K3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	27684187, 31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 347
+	Hs
		1023062 Q6LC01_HUMAN (8-444): 0: 908: 98.86		STK4_HUMAN (42-345): 1.62e-103: 314: 33.12
+	Hs
		428041 TBB5_HUMAN (1-429): 0: 709: 100.00		AKT1_HUMAN (36-345): 1.71e-127: 375: 20.76
+	Hs
		681781 TBB4B_HUMAN (1-427): 0: 707: 98.36		AKT1_HUMAN (36-345): 1.71e-127: 375: 20.76
+	Hs
		805410 TBB3_HUMAN (1-444): 0: 712: 92.57		MP2K3_HUMAN (1-347): 1.73e-124: 362: 100.00
+	Hs
		428148 TBB5_HUMAN (1-429): 0: 709: 100.00		KPCE_HUMAN (3-344): 9.69e-120: 363: 19.89
+	Hs
		933762 TBB4B_HUMAN (1-427): 0: 707: 98.36		KPCE_HUMAN (3-344): 9.69e-120: 363: 19.89
+	Hs
		805387 TBB4B_HUMAN (1-427): 0: 707: 98.36		MP2K3_HUMAN (1-347): 1.73e-124: 362: 100.00
+	Hs
		805414 TBB2A_HUMAN (1-430): 0: 704: 96.98		MP2K3_HUMAN (1-347): 1.73e-124: 362: 100.00
+	Hs
		625344 TBB4B_HUMAN (1-427): 0: 707: 98.36		CDK2_HUMAN (61-336): 3.55e-114: 335: 23.43
+	Hs
		625420 TBB2A_HUMAN (1-430): 0: 704: 96.98		CDK2_HUMAN (61-336): 3.55e-114: 335: 23.43
+	Hs
		933777 TBB4B_HUMAN (1-427): 0: 707: 98.36		STK4_HUMAN (42-345): 1.62e-103: 314: 33.12
+	Ce
		110167 O17921_CAEEL (1-444): 0: 704: 89.64		GCK1_CAEEL (64-330): 2.13e-98: 306: 30.97
+	Ce
		110176 TBB2_CAEEL (1-441): 0: 704: 90.48		GCK1_CAEEL (64-330): 2.13e-98: 306: 30.97
+	Hs
		160334 TBB5_HUMAN (1-429): 0: 709: 100.00		AURKA_HUMAN (1-334): 5.44e-97: 294: 24.70
+	Hs
		160504 TBB4B_HUMAN (1-427): 0: 707: 98.36		AURKA_HUMAN (1-334): 5.44e-97: 294: 24.70
+	Hs
		428177 TBB5_HUMAN (1-429): 0: 709: 100.00		MP2K5_HUMAN (56-324): 7.89e-66: 216: 45.09
+	Hs
		933781 TBB4B_HUMAN (1-427): 0: 707: 98.36		MP2K5_HUMAN (56-324): 7.89e-66: 216: 45.09
+	Hs
		734927 TBB3_HUMAN (1-444): 0: 712: 92.57		MP2K2_HUMAN (49-343): 4.4e-63: 207: 35.78
+	Hs
		428055 TBB5_HUMAN (1-429): 0: 709: 100.00		MP2K2_HUMAN (49-343): 4.4e-63: 207: 35.78
+	Hs
		734912 TBB4B_HUMAN (1-427): 0: 707: 98.36		MP2K2_HUMAN (49-343): 4.4e-63: 207: 35.78