HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.534

Property	Details
Experiments	15324660
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019904 - protein domain specific binding GO:0031625 - ubiquitin protein ligase binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 245
+	Hs
		927013 TBB3_HUMAN (1-444): 0: 712: 92.57		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Bt
		926905 TBB5_BOVIN (1-429): 0: 709: 100.00		1433Z_BOVIN (1-245): 1.67e-144: 405: 100.00
+	Hs
		428127 TBB5_HUMAN (1-429): 0: 709: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Mm
		926824 TBB2A_MOUSE (1-430): 0: 704: 96.98		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Hs
		909434 TBB4B_HUMAN (1-427): 0: 707: 98.36		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		909976 TBB2B_HUMAN (1-430): 0: 707: 97.44		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		927027 TBB2A_HUMAN (1-430): 0: 704: 96.98		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		646872 TBB3_HUMAN (1-444): 0: 712: 92.57		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		428029 TBB5_HUMAN (1-429): 0: 709: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		428042 TBB5_HUMAN (1-429): 0: 709: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		646787 TBB4B_HUMAN (1-427): 0: 707: 98.36		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		646878 TBB2A_HUMAN (1-430): 0: 704: 96.98		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Zm
		77125 B4FTM1_MAIZE (1-430): 0: 697: 86.98		K7U5A5_MAIZE (3-239): 5.22e-139: 392: 62.86
+	Rn
		61830 A6KQR9_RAT (1-427): 0: 702: 97.42		1433B_RAT (1-242): 2e-128: 364: 86.78
+	Hs
		981987 TBB3_HUMAN (1-444): 0: 712: 92.57		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		428124 TBB5_HUMAN (1-429): 0: 709: 100.00		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59