HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 31409757, 35271311
Identification Methods x-ray crystallography, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Tubulin~Tubulin, Tubulin~Tubulin_C, Tubulin_C~Tubulin_C
Common GO terms GO:0000226 - microtubule cytoskeleton organization
GO:0000278 - mitotic cell cycle
GO:0003924 - GTPase activity
GO:0005198 - structural molecule activity
GO:0005200 - structural constituent of cytoskeleton
and 8 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 444
Hs

1 451
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Last updated: 15 Jul 2024