HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0044877 - protein-containing complex binding GO:0046872 - metal ion binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 592
+	Hs
		983829 TBB3_HUMAN (1-444): 0: 712: 92.57		KPCZ_HUMAN (1-592): 0: 688: 100.00
+	Hs
		933766 TBB4B_HUMAN (1-427): 0: 707: 98.36		KPCZ_HUMAN (1-592): 0: 688: 100.00
+	Hs
		983907 TBB6_HUMAN (1-432): 0: 703: 92.13		KPCZ_HUMAN (1-592): 0: 688: 100.00
+	Hs
		381171 TBB4A_HUMAN (1-427): 0: 702: 97.42		KPCZ_HUMAN (1-592): 0: 688: 100.00
+	Hs
		784079 TBB2B_HUMAN (1-430): 0: 707: 97.44		KPCI_HUMAN (1-592): 0: 654: 69.87
+	Hs
		784006 TBB2A_HUMAN (1-430): 0: 704: 96.98		KPCI_HUMAN (1-592): 0: 654: 69.87
+	Hs
		428041 TBB5_HUMAN (1-429): 0: 709: 100.00		AKT1_HUMAN (172-582): 1.55e-153: 451: 36.39
+	Hs
		681781 TBB4B_HUMAN (1-427): 0: 707: 98.36		AKT1_HUMAN (172-582): 1.55e-153: 451: 36.39
+	Hs
		1037424 TBB3_HUMAN (1-444): 0: 712: 92.57		KS6B2_HUMAN (237-590): 1.59e-143: 425: 36.59
+	Hs
		428478 TBB5_HUMAN (1-429): 0: 709: 100.00		KS6B2_HUMAN (237-590): 1.59e-143: 425: 36.59
+	Dm
		1213355 Q8MST5_DROME (1-443): 0: 695: 86.91		AKT1_DROME (181-580): 1.13e-146: 438: 39.06
+	Hs
		381125 TBB4A_HUMAN (1-427): 0: 702: 97.42		KS6B1_HUMAN (227-590): 1.48e-144: 430: 35.60
+	Hs
		934009 TBB4B_HUMAN (1-427): 0: 707: 98.36		KS6B2_HUMAN (237-590): 1.59e-143: 425: 36.59
+	Hs
		568654 TBB3_HUMAN (1-444): 0: 712: 92.57		KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06
+	Hs
		1312829 TBB6_HUMAN (1-432): 0: 703: 92.13		KS6B2_HUMAN (237-590): 1.59e-143: 425: 36.59
+	Hs
		568659 TBB2A_HUMAN (1-430): 0: 704: 96.98		KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06
+	Hs
		428148 TBB5_HUMAN (1-429): 0: 709: 100.00		KPCE_HUMAN (6-196): 1.52e-27: 120: 19.02
+	Hs
		933762 TBB4B_HUMAN (1-427): 0: 707: 98.36		KPCE_HUMAN (6-196): 1.52e-27: 120: 19.02
+	Hs
		969091 TBB8_HUMAN (1-427): 0: 702: 89.70		KPCE_HUMAN (6-196): 1.52e-27: 120: 19.02
+	Hs
		397156 TBB4B_HUMAN (1-427): 0: 707: 98.36		KPCG_HUMAN (116-180): 1.87e-10: 65.9: 36.92