HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	21145461, 32814053
Identification Methods	affinity chromatography technology, tandem affinity purification, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0070062 - extracellular exosome
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 81
+	Dm
		547917 TBB1_DROME (1-429): 0: 705: 96.50		RS27A_DROME (1-77): 3.39e-36: 121: 57.14
+	Ce
		853145 TBB2_CAEEL (1-441): 0: 704: 90.48		NEDD8_CAEEL (1-77): 7.56e-34: 112: 87.01
+	Hs
		933828 TBB4B_HUMAN (1-427): 0: 707: 98.36		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00