HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: M3K14 (Q99558)
Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)
Gene: MAP3K14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 947
+	Hs
		2077 A0A0B4J269_HUMAN (19-444): 0: 825: 92.02		M3K14_HUMAN (1-947): 0: 799: 100.00
+	Hs
		1304514 TBB2B_HUMAN (1-430): 0: 707: 97.44		M3K14_HUMAN (1-947): 0: 799: 100.00
+	Hs
		1023062 Q6LC01_HUMAN (8-444): 0: 908: 98.86		STK4_HUMAN (405-650): 2.6e-99: 321: 30.80
+	Hs
		428041 TBB5_HUMAN (1-429): 0: 709: 100.00		AKT1_HUMAN (286-713): 3.76e-131: 405: 19.33
+	Hs
		681781 TBB4B_HUMAN (1-427): 0: 707: 98.36		AKT1_HUMAN (286-713): 3.76e-131: 405: 19.33
+	Rn
		871318 TBB4B_RAT (1-427): 0: 707: 98.13		AAPK1_RAT (374-909): 5.75e-123: 386: 17.30
+	Hs
		568654 TBB3_HUMAN (1-444): 0: 712: 92.57		KAPCA_HUMAN (361-691): 1.53e-122: 378: 20.46
+	Rn
		871256 TBB2A_RAT (1-430): 0: 704: 96.98		AAPK1_RAT (374-909): 5.75e-123: 386: 17.30
+	Hs
		861738 TBB3_HUMAN (1-444): 0: 712: 92.57		PLK1_HUMAN (406-781): 1.04e-106: 345: 26.87
+	Hs
		1037238 TBB3_HUMAN (1-444): 0: 712: 92.57		KS6A2_HUMAN (319-657): 9e-97: 322: 21.49
+	Hs
		1037241 TBB3_HUMAN (1-444): 0: 712: 92.57		KS6A1_HUMAN (319-695): 1.9e-95: 318: 18.21
+	Hs
		933777 TBB4B_HUMAN (1-427): 0: 707: 98.36		STK4_HUMAN (405-650): 2.6e-99: 321: 30.80
+	Hs
		2076 A0A0B4J269_HUMAN (19-444): 0: 825: 92.02		M3K1_HUMAN (370-643): 2.05e-24: 112: 30.52
+	Hs
		2078 A0A0B4J269_HUMAN (19-444): 0: 825: 92.02		M3K3_HUMAN (373-612): 7.37e-23: 106: 32.14
+	Hs
		428068 TBB5_HUMAN (1-429): 0: 709: 100.00		M3K8_HUMAN (379-647): 2.68e-29: 124: 30.66
+	Hs
		428180 TBB5_HUMAN (1-429): 0: 709: 100.00		M3K1_HUMAN (370-643): 2.05e-24: 112: 30.52
+	Hs
		1028425 TBB2B_HUMAN (1-430): 0: 707: 97.44		M3K1_HUMAN (370-643): 2.05e-24: 112: 30.52
+	Hs
		1037364 TBB3_HUMAN (1-444): 0: 712: 92.57		M3K3_HUMAN (373-612): 7.37e-23: 106: 32.14
+	Hs
		428385 TBB5_HUMAN (1-429): 0: 709: 100.00		M3K3_HUMAN (373-612): 7.37e-23: 106: 32.14
+	Hs
		1306375 TBB2B_HUMAN (1-430): 0: 707: 97.44		M3K3_HUMAN (373-612): 7.37e-23: 106: 32.14